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This edited book focuses on the recent advances in our understanding of age-related macular degeneration (AMD), combining epidemiology and clinical diagnosis, with genetics and immunological aspects as well as the role of proteostasis and mitochondria before diving into new therapies including stem cell based approaches. AMD is a leading cause of largely incurable blindness worldwide and projected to double from 2.07 million to 5.44 million individuals by 2050 in the United States. Globally, 288 million individuals are projected to have AMD by 2040. The disease has enormous socioeconomic impact on the affected individuals, their families and the society. This book will bring together the state of the art basic science knowledge with clinically relevant findings and address the challenges for future research in AMD. The intersection of different disciplines will provide potential areas for further investigations to reduce the burden of blindness from AMD. This book offers an appealing and insightful resource for clinicians, scientists, students and fellows.
ISBN: 9783030660161
Sprache: Englisch
Seitenzahl: 314
Produktart: Kartoniert / Broschiert
Herausgeber: Chew, Emily Y. Swaroop, Anand
Verlag: Springer International Publishing
Veröffentlicht: 15.04.2022
Untertitel: From Clinic to Genes and Back to Patient Management
Schlagworte: Choroid Epidemiology Epigenetics Immunology Incurable blindness Ocular Imaging Stem Cell based Therapies age-related macular degeneration clinical diagnosis proteostasis

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