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The multidisciplinary science of chemical proteomics studies how small molecules of synthetic or natural origin bind to proteins and modulate their function.  In Chemical Proteomics: Methods and Protocols , expert researchers in the field provide key techniques to investigate chemical proteomics focusing on analytical strategies, how probes are generated, techniques for the discovery of small molecule targets and the probing of target function, and small molecule ligand and drug discovery.  Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.   Authoritative and practical, Chemical Proteomics : Methods and Protocols seeks to provide methodologies that will contribute to a wider application of chemical proteomics methods in biochemical and cell biological laboratories.
ISBN: 9781617793639
Sprache: Englisch
Seitenzahl: 313
Produktart: Gebunden
Herausgeber: Bantscheff, Marcus Drewes, Gerard
Verlag: Humana Press
Veröffentlicht: 08.11.2011
Untertitel: Methods and Protocols
Schlagworte: Mass Spectrometry amino acids in cell culture (SILAC) based chemical probes isotope labeling molecule ligand molecules protein function quantitative immunodetection

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