Exon Skipping and Inclusion Therapies
Methods and Protocols
This book presents a comprehensive collection of detailed state-of-the-art exon skipping and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies: Methods and Protocols aims to help researchers initiate the development of next-generation therapies.
| ISBN: | 9781493986507 |
|---|---|
| Sprache: | Englisch |
| Seitenzahl: | 569 |
| Produktart: | Gebunden |
| Herausgeber: | Maruyama, Rika Yokota, Toshifumi |
| Verlag: | Springer US |
| Veröffentlicht: | 01.09.2018 |
| Untertitel: | Methods and Protocols |
| Schlagworte: | Tricyclo-DNA iPS-derived muscle mRNA splicing myotonic dystrophy zebrafish |
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