Immunobiology of Bacterial CpG-DNA
Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.
| ISBN: | 9783642640773 |
|---|---|
| Sprache: | Englisch |
| Seitenzahl: | 246 |
| Produktart: | Kartoniert / Broschiert |
| Herausgeber: | Wagner, H. |
| Verlag: | Springer Berlin |
| Veröffentlicht: | 26.09.2011 |
| Schlagworte: | DNA T cell asthma bacteria cancer cell cytokine cytokines immune response immune system |
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