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Cancer genetics is a field of daunting breadth and depth. The literature describes hundreds of genes and genetic alterations that are variably associated with again as many disease states and risk factors. Integrating these disparate pieces of highly specialized information is challenging for the professional scientist and student alike. This concise guidebook consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer. The book is focused on the most highly representative genes that underlie the most common cancers and highlights new frontiers in gene-based diagnosis and therapy. Primary attention is devoted to the origins of cancer genes and the application of evolutionary theory to explain why the cell clones that harbor cancer genes tend to expand.
Autor: Bunz, Fred
ISBN: 9789048177264
Sprache: Englisch
Seitenzahl: 326
Produktart: Kartoniert / Broschiert
Verlag: Springer Netherland
Veröffentlicht: 19.10.2010
Schlagworte: BRCA Bunz Chromosom Retinoblastom cancer genes genetics mutations transcription

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