Sleep-Wake Neurobiology and Pharmacology
This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions.The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com
| ISBN: | 9783030112707 |
|---|---|
| Sprache: | Englisch |
| Seitenzahl: | 481 |
| Produktart: | Gebunden |
| Herausgeber: | Dijk, Derk-Jan Landolt, Hans-Peter |
| Verlag: | Springer International Publishing |
| Veröffentlicht: | 19.09.2019 |
| Schlagworte: | Circadian rhythms DREADD Optogenetics Pharmacogenetics Receptor pharmacology Sleep Sleep disorders |
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